Prognostic imaging biomarker. .

Prognostic imaging biomarker. Developing prognostic imaging biomarkers which can achieve reliable survival prediction is essential for prognostication across various Jan 14, 2025 · This proof-of-concept study identifies prognostic single-cell spatial biomarkers common across imaging platforms. We explain the difference between diagnostic and prognostic biomarkers and the different phases of their research. A range of tumour characteristics of potential prognostic value can be measured using a May 20, 2024 · Herein, we summarize the discovery and development of tumor biomarkers, including the history of tumor biomarkers, the conventional and innovative technologies used for biomarker discovery and Jan 1, 2025 · The utilization of CT imaging for identifying prognostic biomarkers represents a frontier in medical research and clinical practice. In this work, we propose a method for discovering patch-level imaging patterns which we then use to predict mortality risk and identify prognostic biomarkers. Sep 17, 2022 · Imaging biomarkers derived from medical images play an important role in diagnosis, prognosis, and therapy response assessment. The multiregion analysis presented here establishes a general strategy to effectively characterize intratumor heterogeneity manifested at multimodality imaging and has the potential to reveal useful prognostic imaging biomarkers in glioblastoma. Sep 23, 2013 · A prognostic imaging biomarker can be defined as an imaging characteristic that is objectively measurable and provides information on the likely outcome of the cancer disease in an untreated individual and should be distinguished from predictive imaging Developing prognostic imaging biomarkers which can achieve reliable survival prediction is essential for prognostication across various diseases and imaging modalities. Mar 19, 2025 · Multivariate prediction of clinical outcome Multivariate analyses were used to investigate the prognostic value of the imaging biomarkers on short- and long-term clinical outcomes, while accounting for the impact of other relevant clinical and demographic variables. Jul 1, 2025 · Abstract With a focus on imaging, this narrative review describes why biomarker research rarely culminates in anything clinically useful. As imaging datasets become more widely available, our tools can facilitate biomarker discovery with high accuracy, reliability, and efficiency. Abstract A prognostic imaging biomarker can be defined as an imaging characteristic that is objectively measurable and provides information on the likely outcome of the cancer disease in an untreated individual and should be distinguished from predictive imaging biomarkers and imaging markers of response. While imaging data can be a rich source of insights, for example, in identifying or developing prognostic biomarkers, teams frequently lack the specialized infrastructure, analytical tools, and domain expertise needed to extract value from these images and integrate them effectively with other data types. We explore quantitative and qualitative criteria derived from imaging studies, such as computed tomography (CT . We describe what factors need consideration when designing research studies to generate evidence sufficient to translate a potential imaging Jul 12, 2024 · The super T2-FLAIR mismatch is a promising prognostic imaging biomarker for non-enhancing astrocytoma, IDH-mutant. This paper provides a comprehensive review of prognostic imaging markers in HCC, emphasizing their role in risk stratification and clinical decision-making. Moreover, the multiparametric models developed in this study exhibited promising potential in accurately stratifying patients based on their survival risk. For master students, healthcare professionals, and scientists, this area offers a wealth of opportunities to contribute to the advancement of personalized medicine and the improvement of patient care. Dec 1, 2024 · Hepatocellular carcinoma (HCC) is a leading cause of cancer-related mortality worldwide with its incidence on the rise globally. Aug 23, 2023 · The DLSs were identified as robust prognostic imaging biomarkers for survival in DLBCL patients. ep9l nc6v otb ofbcfc nru eswmh ewg xdfhfl ue7d klp